Methyl Jasmonate is an Effective In Body Treatment for Chronic Lymphocytic Leukemia

This essay is reposted from our subscription blog in the public interest.

Chronic lymphocytic leukemia is the most common form of leukemia. It is considered a fatal disease due to its increasing resistance to chemotherapeutic drugs.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=18515240&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=18358929&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=18247015&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=18024647&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=18159969&itool=pubmed_docsum

A number of years ago, methyl jasmonate, a plant stress hormone, was found to selectively kill chronic lymphotytic leukemia cells in the presence of normal human lymphoid cells. The method of death was apoptosis induced by damage to the leukemic mitochondria. The mitochondria of normal cells was not damaged.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=15753398&itool=pubmed_docsum

Today I received an email from Kathy, a Grouppe Kurosawa Mouse, who purchased methyl jasmonate from us for the treatment of her chronic lymphocytic leukemia. This email speaks for itself.

I was diagnosed in May of 2003 with chronic lymphocytic leukemia and tried and tried to find a 'natural cure' or something that would assist in a cure for my CLL.  My Mom had died of cancer and I swear she died because of what the doctors did to her...and the chemicals.  I didn't want to go that way.  What I have and my Mom had are completely different.  I think too many EMF's cause a lot of cancers.  And lack of sunlight or good D3 (with olive oil) or both. There is no cure for any cancers yet.  So, I did a lot of studying.  When I came accross your site, I knew that "there's a person smart enough, and caring enough to find something soon!"  So, I stuck with your 'cures' until I noticed that the MJ (an SB) seems to work.

My WBC's got as high as 485k before I submitted to the Fludarabine last year.  Its 'cure' only lasted six months.  I thought to use just that after reading the horrid side effects of the other chemicals. In July, before I used the MJ, my WBC was at 285k.  I decided to get to it.  Within the next week or two, the numbers dropped by about 10k or so.  That was at 1x/week (as a steam aerosol treatment).  I got really sick in August and Sept with a throat ailment (cankers in the Esophogus) and my neck nodes swelled to where I looked like a football player.  It was hard to breathe.  Sept., the many docs at the hospital gave me 12mg steroids per day, along with painkiller and antibiotics.  They kept threatening me that if I didn't take my chemo, I'd probably suffocate.  My oncologist lied to me-she said that I would not loose my hair with PCR, Cytotoxin being the culprit.  I'm checking out other docs.  I had taken the steroids and allupurinol for four weeks (approx).  I swelled up like a Campbell Soup doll and was crazy mentally with this stuff.  I did taper off, but I swear that the effects of getting off made me sicker. 

My nodes didn't go down unt il I started doing the MJ more often.  The doc said they wouldn't go down without chemo.   I started using MJ every 3 days, with leftovers in the arm pits with DMSO when there were leftovers.  MJ does irritate my throat.  But, right now, and for three blood tests in a row, my WBC's are down to 23k.  This doesn't usually happen.  It usually shoots back up, and fast.   Every other night, I take a teaspoon of organic bicarbonate of soda and mix with well water.  Usually at bedtime.  Drink fast...it's nasty/salty.   An Italian oncologist says that tumors are fungi gone crazy and to wash them with SB.  I don't have a doc that will give it to me in IV (I have the blood tumor CLL) yet.  It's great for the kidneys if you don't have Allupurinol. But, considering that Linus Pauling uses SB to buffer his high-dose C IV to cure some breast cancers, and that Italian doc, maybe SB and/or MJ is the answer.  Maybe most cancers are just that simple.  After all, MJ is also a fungus killer.  Most synthetic fungal drugs are not only bad for side effects but they don't really work. But, I think my side effects are either from the steroid withdrawal, or the CLL or the MJ, but I can take it...with pain killers sometimes.  It feels like my shoulders are being dislocated.  Maybe it's something different altogether.  I'll be finding a neurologist soon. Since getting off the steroids, I still get a fever almost every day.  Never had that happen.  Usually I sweat it off at night.  Of course, being socked in with over two feet of snow and being freaking freezing...that probably doesn't help.  :) But, this is all I have...and it seems to work.  I think we're on to something...I really do.  Thanks so much for being you, Steve.  Thank you!!!!!!!!!!!!

Kathy, Kurosawa Mouse and New Englander

COMMENT

MJ is a plant defense hormone that does kill fungus. Fungal infections are very difficult to treat in humans, especially in those with damaged immune sytems such as AIDS. Maybe MJ could be useful as a treatment for fungal treatments in humans. I have no idea. Only time will tell.

Stay tuned...

Grouppekurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com

Prostate Cancer and Nutrition

Steve:

 I couldn't let this special day go by without sending this message off to you.  My experience with prostate cancer has been most interesting journey. I was first diagnosed with it about 9 years ago. As you know, PSA is the marker usually used to track progression of the cancer. Mine was about 4.5 at the time of initial diagnosis. The first urologist I had did a biopsy with negative results. Somehow his somber manner and prognosis did not set well with me so I found another very well qualified urologist who had an excellent reputation locally. Again the biopsy but this time a finding of cancer. This was followed by numerous x-rays and a nuclear bone scan to determine if the cancer had spread. Results of that were negative. Thus, the cancer was thought to be local and confined to the prostate. The physician recommended removal of the prostate as the best alternative. Other alternatives were the implant of radioactive seeds and x-ray therapy. There was no discussion of drugs, diet or supplements. I wasn't familiar with the whole subject of PC, so I started on a long path to learn more including visits with several other physicians. Eventually, I decided not to submit to any of the recommended therapy actions - at least not initially.

The Internet and today's searching tools provide a wealth of information. I started to learn more about the effect of diet and the possibility that some supplements might be helpful. One physician I located believed in the use of supplements and made some changes in those as well as my diet. Yet, my PSA continued to climb. Along the way, I found your web site. The information was intriguing. I followed your recommendations, at least in part. Things were going fairly well until fall of 2007 when - soon after I switched from elements of the cytotoxic protocol to the immunotherapy protocol - my PSA increased significantly over a relative short period of time to 10.2. I regrouped, went back to elements of the cytotoxic protocol and started making changes in my supplements while maintaining a fairly restrictive diet with a lot of veggies and not so much fat. I also elected to purchase blood tests from Life Extension so I could track my PSA progress as I made those changes.

I continue to see the urologist every 6 months. There is and has been no evidence of a tumor. I ask the physician about various supplements and over-the-counter drugs such as aspirin and the answer is that from a clinical standpoint, none of those can be recommended. Want selenium? Then I should eat potatoes grown locally. They have a lot of selenium. Yet, surgery is still a good option. I have a lot of doubt about our medical community, at least from my perspective on PC. No need to go into great detail here and now, but some incremental changes in supplements seemed to help while others either made no difference or sent the trend in the wrong direction. My PSA over this year, until recently, was in the range of 9 to 10. In the last month, I made two changes. While I had been consuming dry flax seed for over 2 years, I have started mixing it in oatmeal or other hot cereals before cooking and then proceeded to get it up to temperature with the cereal. The other change, which took place just 2 days before my last PSA test (this time with a different lab) was to switch from Se-Methyl-selenocysteine to sodium selenite. I doubt two days of this could have any impact. Nevertheless, this time the PSA was back down to 8 which is were it was at one point early this year.  But, is the change due to the lab methods or perhaps one of the above mentioned changes? Time will tell. I'll proceed carefully and keep you informed. There is much more to tell, but neither that detail nor the technical content above is the purpose of this message. That last lab result was a nice Christmas present for me. But the fact is that I'd never have known about some of the supplement and diet consequences had it not been for my good fortune in locating your web site. So, here's to thank you for your efforts. Hope this brings some Christmas cheer to you as well. 

Merry Christmas! David

COMMENTARY

As cancers go, there is something unique about prostate cancer that allows it to be controlled by dietary factors. This applies to both the prevention of PC and its treatment. Consider the following.

Pomegranate juice contains a host of polyphenols that directly impair prostate cancer growth. They probably impair the growth of many cancers, but their lnk to controlling prostate cancer growth is well established.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=18237460&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=16479165&itool=pubmed_docsum

The following article can be read online. Click the yellow box. It's a great read.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=18590349&itool=pubmed_docsum

Pomegranate juice is now commonly available in stores. You can also purchase pomegranate wine from a number of suppliers. Pomegranate wine is fabulous if poured over a high quality vanilla ice cream. 

So now you know. 

Stay tuned...

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com